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产品信息
PEP-0847
产品规格
种属反应
Human
分类
Synthetic
类型
Peptide
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
purified
保存液
PBS, pH 7.2, with 0.1% BSA
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
This peptide corresponds to 15 amino acids near the carboxy terminus of human ZBED3.
PEP-0847 can be used as a blocking peptide with polyclonal antibody PA5-20733.
靶标信息
Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression.
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生物信息学
蛋白别名: 2610005H11Rik; Axin-interacting protein; Zinc finger BED domain-containing protein 3; zinc finger, BED domain containing 3; zinc finger, BED-type containing 3
基因别名: ZBED3
UniProt ID: (Human) Q96IU2
Entrez Gene ID: (Human) 84327
