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Invitrogen
Human ZNF609 (aa 54-143) Control Fragment Recombinant Protein
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产品信息
RP-98149
产品规格
种属
Human
Expression System
E. coli
氨基酸序列
SKEVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGANAGGLVAAIAPKGS
标签
His-ABP-tag
分类
Recombinant
类型
Protein
纯度
>80% by SDS-PAGE and Coomassie blue staining
偶联物
形式
Liquid
浓度
≥5.0 mg/mL
纯化类型
purified
保存液
PBS/1M urea, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-59314. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
靶标信息
The ZNF609 gene encodes zinc finger protein 609, which functions as a transcriptional regulator involved in the modulation of gene expression during development and cellular differentiation. ZNF609 contains zinc finger domains, which enable it to bind DNA and control the transcription of target genes, influencing processes such as cell proliferation and neuronal development. This gene is particularly important for normal neural and muscle cell function and has been implicated in neurodevelopmental disorders and cancer. ZNF609 is known to interact with signaling pathways that control neuron differentiation and migration, and alterations in its expression have been associated with conditions like intellectual disability and developmental delay. Furthermore, ZNF609's role in cancer biology shows its involvement in regulating genes linked to tumor progression and metastasis. Studies on ZNF609 focus on understanding its regulatory mechanisms and potential as a therapeutic target for diseases related to developmental deficits and cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Zinc finger protein 609
基因别名: KIAA0295; ZNF609
UniProt ID: (Human) O15014
Entrez Gene ID: (Human) 23060
