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Invitrogen
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Highest antigen sequence indentity to the following orthologs: Mouse (98%), Rat (98%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-56088. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
ZRANB1 is a positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. It acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription and may also modulate TNF-alpha signaling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp762P2216; hTrabid; TRAF-binding domain-containing protein; TRAF-binding protein domain; Ubiquitin thioesterase ZRANB1; Zinc finger Ran-binding domain-containing protein 1; zinc finger, RAN-binding domain containing 1
基因别名: TRABID; ZRANB1
UniProt ID: (Human) Q9UGI0
Entrez Gene ID: (Human) 54764