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Invitrogen
SARS 3CL Protease His-tag Recombinant Protein
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产品信息
RP-88277
产品规格
种属
Virus
Expression System
Baculovirus
氨基酸序列
SARS-CoV-2 3CL protease, amino acids Ser3264-Gln3569 (Accession # YP_009725295.1) with an N-terminal His-tag
标签
His-tag
分子量
37.12 kDa
分类
Recombinant
类型
Protein
纯度
>95% as determined by SDS-PAGE.
内毒素浓度
<1.0 EU/µg
活性
Measured by its ability to cleave a peptide substrate, Dabcyl-KTSAVLQSGFRKME-Edans.The specific activity is >5 pmols/min/ µg;
偶联物
形式
Lyophilized
纯化类型
purified
保存液
20mM tris, pH 8, with 10% glycerol, 0.01% mannitol, 300mM NaCl, 5-8% trehalose, 0.01% Tween 80
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
It is recommended that the protein be aliquoted for optimal storage.
It is recommended that sterile water (400 µL) be added to the vial to prepare a stock solution of 0.25 mg/mL.
Concentration is measured by UV.
靶标信息
Severe Acute Respiratory Syndrome (SARS), an emerging disease characterized by atypical pneumonia, has been attributed to a novel coronavirus (SARS-CoV). The SARS 3C-like protease (SARS 3CL (pro)) is a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for corona virus replication and is considered an attractive target for therapeutics against SARS.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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