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Invitrogen
Basic Human IL-6 Receptor ELISA Kit
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产品规格
检测灵敏度
0.01 ng/mL
测定范围
0.08-5.0 ng/mL
检测样本类型/体积
{Urine=20 µL, Supernatant=20 µL, Plasma=10 µL, Serum=10 µL, Amniotic Fluid=20 µL}
手工操作时间
1 hr 20 min
总时间
2 hr 10 min
均相（无需洗涤）
No
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Sample Diluent
Assay Buffer concentrate
HRP-conjugated Detection Antibody
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Sample Diluent
Assay Buffer concentrate
HRP-conjugated Detection Antibody
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
2-8°C
蛋白名称
IL-6 Receptor (CD126)
均相（无需洗涤）
Human
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
HRP
标签或染料
HRP
关于本试剂盒
Kit Overview
The Human IL-6 Receptor (CD126) ELISA kit enables the quantification of Human IL-6 in various biological samples, including human serum, plasma, buffered solutions, and cell culture medium. This assay is specifically designed to exclusively detect both natural and recombinant forms of Human IL-6 Receptor.
Principle of the assay
The Human IL-6 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) follows a unique approach to measure the amount of the target molecule. It utilizes a matched pair of antibodies to capture the target and form a sandwich complex. The first antibody is pre-coated on the microplate wells, where samples, standards, or controls are added and bind to the immobilized antibody. The second antibody, acting as the detector, is then introduced, followed by the addition of a substrate solution that generates a measurable signal upon interaction with the enzyme-antibody-target complex. The intensity of this signal directly correlates to the concentration of the target present in the original specimen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
靶标信息
Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : CD126, gp80, IL-6R-1, IL-6RA, IL6Q, IL6R, IL6RA, IL6RQ
基因ID : (Human) 3570
基因符号 : IL6R
蛋白别名 : CD126, CD126 antigen, gp80, IL-6 receptor subunit alpha, IL-6 Receptor, il-6 receptor alpha, ILN, Interleukin, MGC104991, IL-6R 1, Interleukin-6 receptor subunit alpha, Membrane glycoprotein 80
UniProt ID (Human) P08887
