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Canine/Human MMP-8 ELISA Kit
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产品规格
检测灵敏度
0.07 ng/mL
测定范围
0.07-50 ng/mL
检测样本类型/体积
{Serum=50 µL, Plasma=50 µL, Supernatant=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
蛋白名称
MMP8
均相（无需洗涤）
Dog
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Canine MMP-8 quantitates canine MMP-8 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant canine MMP-8.
靶标信息
The MMP8 gene encodes matrix metalloproteinase-8, also known as collagenase-2, an enzyme belonging to the matrix metalloproteinase (MMP) family, which plays a pivotal role in the breakdown of extracellular matrix (ECM) components. MMP8 is primarily involved in the degradation of type I and III collagen, facilitating tissue remodeling and repair processes. This enzyme is produced by neutrophils and is active in areas of tissue inflammation and injury, where it modulates the ECM to aid in wound healing. MMP8 is implicated in various physiological processes, including embryonic development, angiogenesis, and bone remodeling. However, excessive or unregulated activity of MMP8 can lead to pathological conditions such as arthritis, periodontal disease, and cancer metastasis, where ECM degradation contributes to disease progression. Research into MMP8 aims to understand its regulation and involvement in disease states, providing insights into potential therapeutic strategies for targeting MMP activity in inflammatory and degenerative conditions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : CLG1, HNC, MMP-8, MMP8, PMNL-CL
基因ID : (Dog) 489429, (Human) 4317
基因符号 : MMP8, MMP8
蛋白别名 : collagenase 2, Collagenase, matrix metallo protease, Matrix metalloproteinase8, MMP, MMP 8, MMPs, PMNL CL, PMNLCL, matrix metallopeptidase 8 (neutrophil collagenase), matrix metalloproteinase 8 (neutrophil collagenase), Matrix metalloproteinase-8, MMP-8, Neutrophil collagenase, PMN leukocyte collagenase, PMNL collagenase, PMNL-CL
UniProt ID (Human) P22894
