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Human ACP6 quantitates human ACP6 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human ACP6.
Lysophosphatidic acid phosphatase type 6 (ACP6), also designated acid phosphatase-like protein 1 (ACPL1) or lysophosphatidic acid phosphatase (LPAP), is a 428 amino acid secreted protein that hydrolyzes lysophosphatidic acid to monoacylglycerol. ACP6 is highly expressed in kidney, heart, small intestine, muscle, liver, prostate, testis, ovary and exists as two isoforms as a result of alternative splicing events. The gene encoding ACP6 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene of human chromosome 1, which encodes lamin A. Stickler syndrome, Parkinsons, Gaucher disease, familial adenomatous polyposis and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : ACP6, ACPL1, LPAP, PACPL1, UNQ205/PRO231
基因ID : (Human) 51205
基因符号 : ACP6
蛋白别名 : 3.1.3.2, Acid phosphatase 6, lysophosphatidic, Acid phosphatase-like protein 1, Lysophosphatidic acid phosphatase type 6, PACPL1
UniProt ID (Human) Q9NPH0