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Human ALK-1 quantitates human ALK-1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human ALK-1.
Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. ACVRL1, similar to other type 1 receptors, has a conserved serine-threonine kinase subdomain, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2. Mutations in ACVRL1 have been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by the formation of bone in muscles, tendons, and other connective tissues, as well as Epicanthus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : ACVRL1, ACVRLK1, ALK-1, ALK1, HHT, HHT2, ORW2, SKR3, TSR-I
基因ID : (Human) 94
基因符号 : ACVRL1
蛋白别名 : activin A receptor type II-like 1, activin A receptor type IL, activin A receptor, type II-like kinase 1, Activin receptor type-1-like, Activin receptor-like kinase 1, ALK-1, Serine/threonine-protein kinase receptor R3, SKR3, TGF-B superfamily receptor type I, TSR-I
UniProt ID (Human) P37023