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Human Activin R2B/ACVR2B quantitates human Activin R2B/ACVR2B in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Activin R2B/ACVR2B.
ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and is involved in the activin and myostatin signaling pathway. Activins and inhibins are members of the TGF-beta superfamily due to amino acid homology with respect to the conservation of 7 of the 9 cysteine residues common to all TGF-beta forms. To date, seven type I and five type II activin receptors have been cloned from mammals, including activin receptor IA, activin receptor IIA, activin receptor IB, and activin receptor IIB. In addition, two splice variants of activin receptor IIA and five splice variants of activin receptor IIB have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : ActR-IIB, ACTRIIB, HTX4
基因ID : (Human) 93
基因符号 : ACVR2B
蛋白别名 : activin A receptor, type IIB, MGC116908, probable match to ACTIVIN RECEPTOR TYPE IIB PRECURSOR (ACTR-IIB)
UniProt ID (Human) Q13705