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The Human Bone Morphogenic Protein 5 (Hu BMP-5) ELISA quantitates Hu BMP-5 in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu BMP-5.
原理方法
The Human BMP-5 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
严格验证
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth, and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling, and maintenance of a variety of other tissues and organs. BMP-5 is expressed in the nervous system, lungs and liver. It is a known regulator for dendritic growth in sympathetic neurons. BMP-5 is a 454 amino acid precursor protein that is cleaved to release the biologically active C-terminal mature protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : BMP5
基因ID : (Human) 653
基因符号 : BMP5
蛋白别名 : BMP-5, BMP, BMP 5, Bone morphogenetic protein, MGC34244, bone morphogenenic protein-5, Bone morphogenetic protein 5
UniProt ID (Human) P22003