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Human CD46 ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of human CD46 in serum, plasma, and cell culture supernatants.
CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : AHUS2, CD46, MCP, MIC10, TLX, TRA2.10
基因ID : (Human) 4179
基因符号 : CD46
蛋白别名 : antigen identified by monoclonal antibody TRA-2-10, CD46, CD46 antigen, complement regulatory protein, CD46 molecule, complement membrane cofactor protein, measles virus receptor, Membrane cofactor protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MGC26544, TLX, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen
UniProt ID (Human) P15529