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Human CRIM1 quantitates human CRIM1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human CRIM1.
CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CRIM-1, CRIM1, S52, UNQ1886/PRO4330
基因ID : (Human) 51232
基因符号 : CRIM1
蛋白别名 : CRIM-1, cysteine rich transmembrane BMP regulator 1 (chordin-like), Cysteine-rich motor neuron 1 protein, Cysteine-rich repeat-containing protein S52
UniProt ID (Human) Q9NZV1