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Invitrogen
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Human Calreticulin quantitates human Calreticulin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Calreticulin.
Calr or Calreticulin is a calcium-binding chaperone that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. Calr, a lectin, interacts transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER. Calr also interacts with with the DNA-binding domain of NR3C1 and mediates its nuclear export. It may also be involved in maternal gene expression regulation and oocyte maturation via the regulation of calcium homeostasis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CALR, cC1qR, CRT, CRTC, HEL-S-99n, RO, SSA
基因ID : (Human) 811
基因符号 : CALR
蛋白别名 : Autoantigen RO, FLJ26680, Ro/SS-A Antigen, Calregulin, Calreticulin, CRP55, Endoplasmic reticulum resident protein 60, epididymis secretory sperm binding protein Li 99n, ERp60, grp60, HACBP, Sicca syndrome antigen A (autoantigen Ro, calreticulin)
UniProt ID (Human) P27797