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Human Carboxylesterase 1/CES1 quantitates human Carboxylesterase 1/CES1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Carboxylesterase 1/CES1.
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : ACAT, CE-1, CEH, CES2, hCE-1, HMSE, HMSE1, PCE-1, REH, SES1, TGH
基因ID : (Human) 1066
基因符号 : CES1
蛋白别名 : acyl coenzyme A:cholesterol acyltransferase, brain carboxylesterase hBr1, carboxylesterase 1 (monocyte/macrophage serine esterase 1), carboxylesterase 2 (liver), carboxylesterase, ACAT, cholesteryl ester hydrolase, cocaine carboxylesterase, egasyn, ER-resident carboxylesterase, human monocyte/macrophage serine esterase 1, methylumbelliferyl-acetate deacetylase 1, MGC117365, triacylglycero, monocyte/macrophage serine esterase, retinyl ester hydrolase, serine esterase 1, triacylglycerol hydrolase, unnamed protein product
UniProt ID (Human) P23141