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Invitrogen
Human Cathepsin D ELISA Kit
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产品规格
检测灵敏度
0.049 ng/mL
测定范围
0.049-12 ng/mL
检测样本类型/体积
{Serum=50 µL, Plasma=50 µL, Supernatant=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
蛋白名称
Cathepsin D
均相（无需洗涤）
Human
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Human Cathepsin D quantitates human Cathepsin D in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Cathepsin D.
靶标信息
Cathepsin D is a gene located on chromosome 11p15.5 that encodes a lysosomal aspartic protease involved in the degradation of proteins. This enzyme is widely expressed in various tissues but is particularly abundant in the liver, kidneys, and brain, where it plays a crucial role in intracellular protein catabolism and turnover. Cathepsin D is synthesized as an inactive precursor, procathepsin D, which is activated in the acidic environment of lysosomes. Beyond its fundamental role in protein degradation, Cathepsin D has been implicated in several physiological and pathological processes, including apoptosis, hormone processing, and antigen presentation. Dysregulation of Cathepsin D expression or activity is associated with various diseases, such as neurodegenerative disorders, cancer, and cardiovascular diseases. In the context of cancer, Cathepsin D overexpression has been linked to tumor progression and metastasis, making it a potential biomarker and therapeutic target. Research continues to explore its diverse biological functions and therapeutic implications in various medical conditions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : CLN10, CPSD, CTSD, HEL-S-130P
基因ID : (Human) 1509
基因符号 : CTSD
蛋白别名 : Cathepsin D, CathepsinD, Ceroid lipofuscinosis neuronal 10, MGC2311, OTTHUMP00000196039, OTTHUMP00000198692, ceroid-lipofuscinosis, neuronal 10, epididymis secretory sperm binding protein Li 130P, lysosomal aspartyl peptidase, lysosomal aspartyl protease
UniProt ID (Human) P07339
