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Human Contactin-2/TAG1 quantitates human Contactin-2/TAG1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Contactin-2/TAG1.
Contactin 2 (CNTN2, transiently-expressed axonal glycoprotein, AXT, TAX, TAX1, TAG-1, axonin 1) is a neuronal cell adhesion molecule (CAM) that influences the formation of axon connections in the developing nervous system. Contactin 2 is a member of the immunoglobulin superfamily (IgSF) and contains a glycosylphosphatidylinositol-anchor, six immunoglobulin (Ig)-like and four Fibronectin type III (FNIII)-like domains. Contactin 2 is expressed predominantly during neural development on the cell membrane of axons in nerve fiber tracts in order to guide commissural axons without promoting their growth. Contactin 2 binds with NgCAM in the plane of the same membrane (cis-binding). The Contactin 2 heterophilic (Contactin 2/NgCAM and Contactin 2/NrCAM) binding sites are localized to the first four Ig domains. The Contactin 2 homophilic (Contactin 2/Contactin 2) binding site is localized to the FNIII domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : AXT, CNTN2, FAME5, TAG-1, TAG1, TAX, TAX1
基因ID : (Human) 6900
基因符号 : CNTN2
蛋白别名 : Axonal glycoprotein TAG-1, Axonin 1, Axonin1, Contactin2, DKFZp781D102, MGC157722, Axonin-1, axonin-1 cell adhesion molecule, contactin 2 (axonal), contactin 2 (transiently expressed), Contactin-2, TAX-1, Transient axonal glycoprotein 1, transiently-expressed axonal glycoprotein
UniProt ID (Human) Q02246