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Invitrogen
Human Cytokeratin 18/KRT18 ELISA Kit
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产品规格
检测灵敏度
0.164 ng/mL
测定范围
0.164-40 ng/mL
检测样本类型/体积
{Plasma=50 µL, Serum=50 µL, Supernatant=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
蛋白名称
Cytokeratin 18
均相（无需洗涤）
Human
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Human CytokeRatin 18/KRT18 quantitates human Cytokeratin 18/KRT18 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Cytokeratin 18/KRT18.
靶标信息
Cytokeratin 18 (Keratin 18, KRT18, type I cytoskeletal 18) belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18. Further, cytokeratin 18 is found primarily in non-squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas, but not in squamous cell carcinomas. Hepatocellular carcinomas express only cytokeratins 8 and 18. Mutations in the cytokeratin 18 gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for the cytokeratin 18 gene. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
基因别名 : CK-18, CYK18, K18, KRT18, PIG46
基因ID : (Human) 3875
基因符号 : KRT18
蛋白别名 : Cell proliferation-inducing gene 46 protein, CK 18, Cytokeratin18, K 18, Keratin18, KRT 18, type I cytoskeletal 18, CK-18, cytokeratin 18, Cytokeratin-18, K18, keratin 18, type I, Keratin, Keratin-18
UniProt ID (Human) P05783
