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Human DC-SIGNR/CD299 quantitates human DC-SIGNR/CD299 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human DC-SIGNR/CD299.
CLEC4M is a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CD209L, CD209L1, CD299, CLEC4M, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, L-SIGN, LSIGN
基因ID : (Human) 10332
基因符号 : CLEC4M
蛋白别名 : C-type lectin domain family 4 member M, C-type lectin domain family 4, member M, CD209 antigen-like protein 1, CD299, CD299 antigen, DC-SIGN-related protein, DC-SIGN2, DC-SIGNR, Dendritic cell-specific ICAM-3-grabbing non-integrin 2, L-SIGN, liver/lymph node-specific ICAM-3 grabbing non-integrin, Liver/lymph node-specific ICAM-3-grabbing non-integrin, mannose binding C-type lectin DC-SIGNR, MGC129964, MGC47866
UniProt ID (Human) Q9H2X3