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Human DC-SIGNR/CD299 quantitates human DC-SIGNR/CD299 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human DC-SIGNR/CD299.
CLEC4M is a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a type II integral membrane protein that is 77% identical to CD209 antigen, a HIV gp120-binding protein. This protein, like CD209, efficiently binds both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. This gene is mapped to 19p13.3, in a cluster with the CD209 and CD23/FCER2 genes. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : CD209L, CD209L1, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, L-SIGN, LSIGN
基因ID : (Human) 10332
基因符号 : CLEC4M
蛋白别名 : C-type lectin, CD209 antigen-like protein 1, CD299 antigen, DC-SIGN-related protein, dendritic cell-specific ICAM-3-grabbing non-integrin 2, liver/lymph node-specific ICAM-3 grabbing non-integrin, mannose binding C-type lectin DC-SIGNR, MGC129964, MGC47866, type II integral membrane protein, unnamed protein product
UniProt ID (Human) Q9H2X3