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Human Desmocollin 2 ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of human Desmocollin-2 in serum, plasma, and cell culture supernatants.
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : ARVD11, CDHF2, DG2, DGII/III, DSC3
基因ID : (Human) 1824
基因符号 : DSC2
蛋白别名 : ARVC10, ARVD10, CDHF5, CDHF6, CMD1BB, desmoglein-2, desmoglein-3, HDGC, PVA, cadherin family member 2, desmosomal glycoprotein II/III, desmosomal protein, unnamed protein product
UniProt ID (Human) Q02487