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Human Desmocollin 2 ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of human Desmocollin-2 in serum, plasma, and cell culture supernatants.
This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : ARVD11, CDHF2, DG2, DGII/III, DSC2, DSC3
基因ID : (Human) 1824
基因符号 : DSC2
蛋白别名 : ARVC10, ARVD10, CDHF5, CDHF6, CMD1BB, desmoglein-2, desmoglein-3, HDGC, PVA, Cadherin family member 2, Desmocollin-2, Desmocollin-3, Desmosomal glycoprotein II, desmosomal glycoprotein II/III, Desmosomal glycoprotein III
UniProt ID (Human) Q02487