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产品规格
检测灵敏度
Lot-specific
测定范围
Lot-specific
手工操作时间
1 hr 45 min
总时间
24 hr 30 min
均相（无需洗涤）
No
检测仪器
Absorbance Microplate Reader
产品规格
10 x 96 Tests
产品成分
This Human FGF2 ELISA Kit includes Capture Antibody, Detection Antibody, Protein Standard, and HRP-conjugate. The HRP-conjugate is packaged separately.
储存
Refer to product documentation for component specific storage temperature.
蛋白名称
FGF2
蛋白家族
Growth Factors & Receptors
均相（无需洗涤）
Human
检测试剂盒格式
ELISA Development Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
900-K08K consists of: 900-K08 (capture antibody, detection antibody, and protein standard), and AVIDIN-60UL (avidin HRP-conjugate).
Human FGF2 ABTS ELISA Development Kit contains the key components required for the quantitative measurement of natural and/or recombinant human FGF2 in a sandwich ELISA format. Human FGF2 ABTS ELISA Development Kit contains enough material to assay the target cytokine in at least 1,000 ELISA plate wells.
The ABTS ELISA Buffer Kit (Product # 900-K00), sold separately, is recommended to be used in conjunction with this ABTS ELISA Development Kit for optimal performance. This buffer kit contains all the necessary components to assay ten 96-well ELISA plates (included) and contains detailed handling instructions.
靶标信息
FGF2 (FGFb, fibroblast growth factor basic) belongs to the fibroblast growth factor (FGF) family, and interacts with high-affinity transmembrane receptors to influence cell proliferation and tissue neovascularization. FGF2 exists as five isoforms with distinct intracellular localizations and functions. The 18 kDa isoform is predominantly cytosolic and acts through cell surface receptors, whereas the 22, 22.5, 24 and 34 kDa isoforms are nuclear and may signal independent of transmembrane receptor pathways. In humans, the gene is located on the q arm of chromosome 4. FGF2 has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for FGF2 contains multiple polyadenylation sites, and is alternatively translated from non-AUG and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. Diseases associated with FGF2 dysfunction include Kaposi Sarcoma and corneal neovascularization.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
基因别名 : BFGF, FGF-2, FGF2, FGFB, HBGF-2
基因ID : (Human) 2247
基因符号 : FGF2
蛋白别名 : Basic fibroblast growth factor, basic fibroblast growth factor bFGF, bFGF, FGF, fgf basic, FGF-b, Fibroblast growth factor, Fibroblast growth factor basic, H-FGF-b-147, H-FGF-b-154, M-FGF-b, FGF-2, Fibroblast growth factor 2, fibroblast growth factor 2 (basic), HBGF-2, Heparin-binding growth factor 2, prostatropin
UniProt ID (Human) P09038
