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Human FKBP12 ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of human FKBP12 in serum, plasma, and cell culture supernatants.
FKBP12 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE
基因ID : (Human) 2280
基因符号 : FKBP1A
蛋白别名 : 12 kDa FK506-binding protein, 12 kDa FKBP, calstabin-1, EC 5.2.1.8, FK506 binding protein 1A, 12kDa, FK506 binding protein12, FK506-binding protein (FKBP), FK506-binding protein 1, FK506-binding protein 12, FK506-binding protein 1A, FK506-binding protein, T-cell, 12-kD, FKBP12-Exip3, FKBP1A, immunophilin FKBP12, PPIase FKBP1A, protein kinase C inhibitor 2, rotamase
UniProt ID (Human) P62942