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Human GLI-3 quantitates human GLI-3 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human GLI-3.
This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : ACLS, GCPS, GLI3, GLI3-190, GLI3FL, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV
基因ID : (Human) 2737
基因符号 : GLI3
蛋白别名 : GLI-Kruppel family member GLI3, GLI3 form of 190 kDa, GLI3 full-length protein, GLI3-190, GLI3FL, glioma-associated oncogene family zinc finger 3, oncogene GLI3, Transcriptional activator GLI3, zinc finger protein GLI3
UniProt ID (Human) P10071