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Human GPR56 quantitates human GPR56 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human GPR56.
GPR56 is a member of the G protein-coupled receptor family. The protein contains 7 transmembrane domains and a mucin-like domain in the N-terminal region. The gene is implicated in the regulation of brain cortical patterning. The protein binds specifically to transglutaminase 2 in the extracellular space. Expression of this gene is downregulated in melanoma cell lines, and overexpression of this gene can suppress tumor growth and metastasis. Mutations in this gene result in bilateral frontoparietal polymicrogyria. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : ADGRG1, BFPP, BPPR, GPR56, TM7LN4, TM7XN1, UNQ540/PRO1083
基因ID : (Human) 9289
基因符号 : ADGRG1
蛋白别名 : 7-transmembrane protein with no EGF-like N-terminal domains-1, Adhesion G-protein coupled receptor G1, Cyt28, DKFZp781L1398, G protein-coupled receptor 56, G-protein coupled receptor 56, Protein TM7XN1, testicular tissue protein Li 77
UniProt ID (Human) Q9Y653