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Human Hemoglobin quantitates human Hemoglobin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Hemoglobin.
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : beta-globin, CD113t-C, ECYT6, ECYT7, HBA-T3, HBA1, HBA2, HBB, HBH, METHBA
基因ID : (Human) 3039, (Human) 3043
基因符号 : HBA1, HBB
蛋白别名 : alpha globin chain, alpha one globin, alpha-1 globin, alpha-1-globin, ALPHA-GLOBIN GENE, Haemoglobin, Hb, HbA1c, alpha-2 globin chain, Alpha-globin, beta globin, beta globin chain, Beta-globin, delta globin, Hb Monza protein, HBB, hemoglobin, hemoglobin alpha 1 globin chain, Hemoglobin alpha chain, Hemoglobin beta chain, hemoglobin beta subunit, Hemoglobin subunit alpha, Hemoglobin subunit beta, alpha 1, beta, sickle beta-hemoglobin, unnamed protein product, unstable hemoglobin, hemoglobin 'Louisville'
UniProt ID (Human) P69905, (Human) P68871