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The Human Fibrinogen Like Protein 1 (FGL1) ELISA quantitates FGL1 in serum, plasma, and other biological fluids
The Human Fibrinogen Like Protein 1 (FGL1) solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the binding of the second (detector) antibody to the target on a different epitope from the capture antibody. An antibody conjugated with enzyme binds the formed sandwich. After incubation and washing steps to rid the microplate of unbound substances, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
Rigorous validation:
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : FGL1, HFREP1, HP-041, LFIRE-1, LFIRE1
基因ID : (Human) 2267
基因符号 : FGL1
蛋白别名 : fibrinogen-like 1, Fibrinogen-like protein 1, Hepassocin, hepatocellular carcinoma-related sequence, Hepatocyte-derived fibrinogen-related protein 1, HFREP-1, HP-041, HPS, LFIRE-1, Liver fibrinogen-related protein 1, MGC12455, OTTHUMP00000122468
UniProt ID (Human) Q08830