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The Human I-309/CCL1 ELISA quantitates Hu I-309 in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu I-309.
原理方法
The Human I-309 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
严格验证
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CCL1, I-309, P500, SCYA1, SISe, TCA3
基因ID : (Human) 6346
基因符号 : CCL1
蛋白别名 : C-C motif chemokine 1, chemokine (C-C motif) ligand 1, inflammatory cytokine I-309, small inducible cytokine A1 (I-309, homologous to mouse Tca-3), Small-inducible cytokine A1, T lymphocyte-secreted protein I-309, CCL 1
UniProt ID (Human) P22362