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Human IL-17 RB quantitates human IL-17 RB in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human IL-17 RB.
Recently, a number of cytokines belonging to the interleukin (IL)-17 family have been identified. These are termed as IL-17B, IL-17C (1) and IL-17E. IL-17 is a potent proinflammatory cytokine that plays roles in a number of diseases including rheumatoid arthritis, multiple sclerosis, and promotion of tumor growth. IL-17B, C, and E like IL-17 are able to induce proinflammatory responses. However, they do not bind to the IL-17 receptor suggesting that additional IL-17R related receptor might exist. Receptor for IL-17B and IL-17E has been independently isolated and has been designated as EV127 (in mouse) and IL-17Rh1 (in human), respectively. IL-17E induces activation of NF-kB pathway and like IL-17 also induces production of IL-8. IL-17Rh1 mRNA is highly expressed in Kidney and liver and at moderate level in small intestine, colon, and brain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CRL4, EVI27, IL17BR, IL17RB, IL17RH1, UNQ2501/PRO19612
基因ID : (Human) 55540
基因符号 : IL17RB
蛋白别名 : cytokine receptor CRL4, Cytokine receptor-like 4, IL-17 receptor B, IL-17 receptor homolog 1, IL-17B receptor, IL-17B, IL-20, MGC138900, MGC138901, MGC5245, ZCYTO7, IL-17RB, IL-17Rh1, interleukin 17 receptor homolog 1, interleukin 17B receptor, Interleukin-17 receptor B, Interleukin-17B receptor
UniProt ID (Human) Q9NRM6