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The Human Interleukin 18 Receptor Beta (Hu IL-18RB) (IL-18RAP) ELISA quantitates Hu IL-18RB in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu IL-18RB.
原理方法
The Human IL-18RB solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
严格验证
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : ACPL, CD218b, CDw218b, IL-18R-beta, IL-18RAcP, IL-18Rbeta, IL-1R-7, IL-1R7, IL-1RAcPL, IL18RAP, IL18RB, IL1R7
基因ID : (Human) 8807
基因符号 : IL18RAP
蛋白别名 : Accessory protein-like, AcPL, CD218 antigen-like family member B, CD218b, CDw218b, cluster of differentiation w218b, IL-18 RA, IL-18 receptor accessory protein, IL-18 receptor beta, IL-18R-beta, IL-1R accessory protein-like, IL-1R-7, IL-1RAcPL, Interleukin-1 receptor 7, Interleukin-18 receptor accessory protein, Interleukin-18 receptor accessory protein-like, Interleukin-18 receptor beta
UniProt ID (Human) O95256