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The Human Kallikrein 6 (Hu KLK6) ELISA quantitates Hu KLK6 in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu KLK6.
原理方法
The Human KLK6 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
严格验证
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
Kallikreins, including Kallikrein 6, are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The KLK6 enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : Bssp, hK6, KLK6, Klk7, PRSS18, PRSS9, SP59
基因ID : (Human) 5653
基因符号 : KLK6
蛋白别名 : kallikrein 6, Kallikrein-6, Neurosin, Protease M, SP59, Serine protease 18, Serine protease 9, Zyme, kallikrein 7, Kallikrein6, MGC9355
UniProt ID (Human) Q92876