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Invitrogen
Human Legumain ELISA Kit
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产品规格
检测灵敏度
28.7 pg/mL
测定范围
28.7-7,000 pg/mL
检测样本类型/体积
{Supernatant=50 µL, Serum=50 µL, Plasma=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
蛋白名称
LGMN
均相（无需洗涤）
Human
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Human Legumain quantitates human Legumain in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Legumain.
靶标信息
This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : AEP, LGMN, LGMN1, PRSC1
基因ID : (Human) 5641
基因符号 : LGMN
蛋白别名 : AEP, Asparaginyl endopeptidase, cysteine protease 1, Legumain, Protease, cysteine 1, protease, cysteine, 1 (legumain), PRSC1EC 3.4.22.34
UniProt ID (Human) Q99538
