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Human Lp-PLA2/PLA2G7/PAF-AH quantitates human Lp-PLA2/PLA2G7/PAF-AH in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Lp-PLA2/PLA2G7/PAF-AH.
Platelet Activating Factor (PAF) is a biologically active phospholipid, which exerts primarily proinflammatory activities by specifically signaling through G-protein-coupled receptors on platelets, neutrophils, and monocytes. Platelet Activating Factor Acetylhydrolase (PAF-AH) is a secreted protein that mediates PAF activity by specifically catalyzing hydrolysis of the "sn2" ester bond, resulting in the conversion of PAF to the biologically inactive lyso-PAF. PAF-AH can also interact with LDL particles to induce the hydrolysis of LDL-associated, oxidized phospholipids, generating lysophosphatidylcholine (lyso-PC) and other lysophospholipids.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : LDL-PLA2, LP-PLA2, PAFAD, PAFAH, PLA2G7
基因ID : (Human) 7941
基因符号 : PLA2G7
蛋白别名 : 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, Group-VIIA phospholipase A2, gVIIA-PLA2, LDL-associated phospholipase A2, LDL-PLA(2), lipoprotein-associated phospholipase A2, PAF 2-acylhydrolase, PAF acetylhydrolase, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma), Platelet-activating factor acetylhydrolase
UniProt ID (Human) Q13093