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The Human Lymphotactin XCL1 ELISA quantitates Hu Lymphotactin in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu Lymphotactin.
原理方法
The Human Lymphotactin solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
严格验证
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
Lymphotactin, otherwise known as XCL1, is a member of the C-chemokine family that uniquely acts as a chemoattractant for lymphocytes, but not monocytes or neutrophils, suggesting an important regulatory role in lymphocyte trafficking and inflammation. Lymphotactin, shown to signal through chemokine XC receptor 1 (XCR1), is detected at the highest level in the spleen and at low levels in the lungs, small intestine and colon, and is abundantly and selectively expressed by activated T cells, in particular CD8+ T cells, and is also produced by NK cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : ATAC, LPTN, LTN, SCM-1, SCM-1a, SCM1, SCM1A, SCYC1, XCL1
基因ID : (Human) 6375
基因符号 : XCL1
蛋白别名 : ATAC, C motif chemokine 1, chemokine (C motif) ligand 1, Cytokine SCM-1, Lymphotactin, Lymphotaxin, SCM-1-alpha, SCM1alpha, SCM-1alpha, SCM1beta, SCM-1beta, SCM-1-beta, single cysteine motif 1a, small inducible cytokine subfamily C, member 1 (lymphotactin), Small-inducible cytokine C1, XC chemokine ligand 1
UniProt ID (Human) P47992