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Human MFG-E8 quantitates human MFG-E8 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human MFG-E8.
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : BA46, EDIL1, HMFG, hP47, HsT19888, MFG-E8, MFGE8, MFGM, OAcGD3S, SED1, SPAG10
基因ID : (Human) 4240
基因符号 : MFGE8
蛋白别名 : Breast epithelial antigen BA46, HMFG, Lactadherin, medin, MFG-E8, MFGM, milk fat globule membrane, milk fat globule membrane protein, Milk fat globule-EGF factor 8, O-acetyl disialoganglioside synthase, SED1, sperm associated antigen 10, sperm surface protein hP47
UniProt ID (Human) Q08431