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Human MZB1 ELISA Kit is an enzyme-linked immunosorbent assay for quantitative detection of human MZB1 in serum, plasma, and cell culture supernatants.
MZB1 associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity. Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation.; Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : HSPC190, MEDA-7, MEDA7, MZB1, PACAP, pERp1
基因ID : (Human) 51237
基因符号 : MZB1
蛋白别名 : caspase-2 binding protein, HSPC190, marginal zone B and B1 cell-specific protein, Marginal zone B- and B1-cell-specific protein, MEDA-7, Mesenteric estrogen-dependent adipose 7, mesenteric oestrogen-dependent adipose gene- 7, MGC29506, plasma cell-induced ER protein 1, Plasma cell-induced resident endoplasmic reticulum protein, Plasma cell-induced resident ER protein, Proapoptotic caspase adapter protein, proapoptotic caspase adaptor protein
UniProt ID (Human) Q8WU39