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Mouse BCL-W quantitates mouse BCL-W in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse BCL-W.
Using a PCR-based strategy, an additional protein with life-promoting activity, designated Bcl-w, has been identified. The protein is highly conserved between mouse and human and is encoded by a gene located near the TCRalpha gene on chromosome 14. Bcl-w is expressed in myeloid cell lines but not in T and B lymphocytes, and can be found in a wide range of tissues. An alternative splicing event in exon 4 results in two transcripts. The first, Bcl-w, encodes a protein of 193 amino acids, and the second, Bcl-w/rox, encodes a protein 333 amino acids in length. The "rox" portion of Bcl-w/rox shows a striking 66% amino acid sequence identity with the Drosophila rox2 protein; however, the Bcl-w/rox transcript may be expressed at very low levels.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : AW048834, BCL-W, BCL2-L-2, BCL2L2, BCLW, c98, Gtrgal2, Gtrosa41, KIAA0271, PPP1R51
基因ID : (Human) 599, (Mouse) 12050
基因符号 : BCL2L2, Bcl2l2
蛋白别名 : Apoptosis regulator Bcl-W, Bcl-2-like protein 2, Bcl2-L-2, BCL2-like 2 protein, Bcl2-like protein 2, c98, protein phosphatase 1, regulatory subunit 51
UniProt ID (Human) Q92843, (Mouse) P70345