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Invitrogen
Human/Mouse COCO ELISA Kit
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产品规格
检测灵敏度
0.2 ng/mL
测定范围
0.2-50 ng/mL
检测样本类型/体积
{Plasma=50 µL, Serum=50 µL, Supernatant=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
蛋白名称
DAND5
均相（无需洗涤）
Human
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Human COCO quantitates human COCO in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human COCO.
靶标信息
This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. In mouse, this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : CER2, Cerl-2, CERL2, Cerr2, CKTSF1B3, COCO, CRL2, DAND5, DANTE, Dte, GREM3, SP1
基因ID : (Human) 199699, (Mouse) 23863
基因符号 : DAND5, Dand5
蛋白别名 : CER2CRL2, Cerberus like-2, CKTSF1B3MGC126849, FLJ38607, GREM3cerberus 2, MGC126849, cerberus 2, cerberus-like 2, Cerberus-like protein 2, Cerl-2, Cysteine knot superfamily 1, BMP antagonist 3, DAN domain family member 5, BMP antagonist, DAN domain family, member 5, dante, Gremlin-3
UniProt ID (Human) Q8N907, (Mouse) Q76LW6
