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Invitrogen
Human Norrin ELISA Kit
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产品规格
检测灵敏度
0.41 ng/mL
测定范围
0.41-100 ng/mL
检测样本类型/体积
{Supernatant=50 µL, Serum=50 µL, Plasma=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
蛋白名称
NDP
均相（无需洗涤）
Human
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Human Norrin quantitates human Norrin in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Norrin.
靶标信息
NDP (Norrie disease protein), also known as norrin, is a secreted signaling protein encoded by the NDP gene that activates the canonical Wnt/β-catenin pathway by binding the Frizzled-4 (FZD4)/LRP5 receptor complex. It plays an essential role in retinal vascular development, maintenance of the blood-retina barrier, and inner ear vascularization. Loss-of-function variants in NDP cause Norrie disease and can also contribute to familial exudative vitreoretinopathy (FEVR).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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生物信息学
基因别名 : EVR2, FEVR, ND
基因ID : (Human) 4693
基因符号 : NDP
蛋白别名 : NDP, norrin cystine knot growth factor, Norrie disease (pseudoglioma), norrie disease protein, unnamed protein product, X-linked exudative vitreoretinopathy 2 protein
UniProt ID (Human) Q00604
