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The Human Osteoprotegerin Rapid ELISA Kit quantitates TNFRSF11B in serum and plasma
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : OCIF, OPG, PDB5, TNFRSF11B, TR1
基因ID : (Human) 4982
基因符号 : TNFRSF11B
蛋白别名 : MGC29565, soluble OPG, soluble Osteoprotegerin, sOPG, OPG, Osteoclastogenesis inhibitory factor, Osteoprotegerin, Tumor necrosis factor receptor superfamily member 11B, tumor necrosis factor receptor superfamily, member 11b, unnamed protein product
UniProt ID (Human) O00300