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Invitrogen
Human PON1 ELISA Kit
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产品规格
检测灵敏度
0.2 ng/mL
测定范围
0.2-50 ng/mL
检测样本类型/体积
{Supernatant=50 µL, Serum=50 µL, Plasma=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
蛋白名称
PON1
均相（无需洗涤）
Human
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Human PON1 quantitates human PON1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human PON1.
靶标信息
The paraoxonase (PON) gene-family in humans has three members, PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3-22.1. PON1 of these is synthesized primarily in the liver and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). And It hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
基因别名 : ESA, MVCD5, PON, PON1
基因ID : (Human) 5444
基因符号 : PON1
蛋白别名 : A esterase 1, EC 3.1.1.2, EC 3.1.1.81, EC 3.1.8.1, ESAesterase A, A-esterase 1, Aromatic esterase 1, arylesterase 1, arylesterase B-type, esterase A, K-45, paraoxonase B-type, PON 1, serum aryldiakylphosphatase, Serum aryldialkylphosphatase 1, Serum paraoxonase/arylesterase 1
UniProt ID (Human) P27169
