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The Human RAGE (Hu MOK) ELISA quantitates Hu MOK in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu MOK.
原理方法
The Human MOK solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
严格验证
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
MOK is able to phosphorylate several exogenous substrates and to undergo autophosphorylation. It negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : MOK, RAGE, RAGE-1, RAGE1, STK30
基因ID : (Human) 5891
基因符号 : MOK
蛋白别名 : MAPK/MAK/MRK overlapping kinase, MOK protein kinase, Renal tumor antigen 1, RAGE-1, soluble RAGE, renal cell carcinoma antigen
UniProt ID (Human) Q9UQ07