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Monkey MCP-1/CCL2 quantitates monkey MCP-1/CCL2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant monkey MCP-1/CCL2.
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF
基因ID : (Human) 6347
基因符号 : CCL2
蛋白别名 : C-C motif chemokine 2, chemokine (C-C motif) ligand 2, chemotactic and activating factor precursor, Genbank Staff Annotation: The small inducible cytokine A2 (SWISS-PROT ACC P13500) is encoded in this mRNA, although it is interrupted and partial, perhaps indicating that this CDS is not the true product of the gamma.1 gene., H-MCP-1, MGC9434, RP23-350G1.3, HC11, MCAF, MCP-1, Monocyte chemoattractant protein 1, monocyte chemoattractant protein-1, Monocyte chemotactic and activating factor, monocyte chemotactic protein, Monocyte chemotactic protein 1, Monocyte secretory protein JE, Mutations: 171:OK, small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je), small inducible cytokine subfamily A (Cys-Cys), member 2, Small-inducible cytokine A2, unnamed protein product
UniProt ID (Human) P13500