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Human S100 A7 quantitates human S100 A7 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human S100 A7.
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : PSOR1, S100A7, S100A7C
基因ID : (Human) 6278
基因符号 : S100A7
蛋白别名 : Protein S100-A7, Psoriasin, psoriasin 1, S100 calcium-binding protein A7, S100 calcium-binding protein A7 (psoriasin 1)
UniProt ID (Human) P31151