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Invitrogen
Human SIRT1 ELISA Kit
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产品规格
检测灵敏度
1.23 ng/mL
测定范围
1.23-300 ng/mL
检测样本类型/体积
{Serum=50 µL, Supernatant=50 µL, Plasma=50 µL}
手工操作时间
1 hr 20 min
总时间
4 hr 45 min
均相（无需洗涤）
No
批间差异
<12%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated 96 well plate
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
Standard
Assay Diluent concentrate
Biotinylated Detection Antibody
SAV-HRP
Wash Buffer
Chromogen
Stop Solution
Adhesive Plate Covers
运输条件
Wet ice
储存
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
蛋白名称
SIRT1
均相（无需洗涤）
Human
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
Human SIRT1 quantitates human SIRT1 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human SIRT1.
靶标信息
NAD-dependent protein deacetylase sirtuin-1 (SIRT1) links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, repsonse to DNA damage, metabolism, apoptosis, and autophagy. SIRT1 can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histone and DNA, leading to transcriptional repression. It is essential in skeletal muscle cell differentiation and in response to low nutrients mediates the inhibitory effect on skeletal myoblast differentiation which also involves 5'-AMP-activated protein kinase (AMPK) and nicotinamide phosphoribosyltransferase (NAMPT).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
生物信息学
基因别名 : SIR2, SIR2alpha, SIR2L1
基因ID : (Human) 23411
基因符号 : SIRT1
蛋白别名 : domain has histone deacetylase activity, NAD-dependent protein deacylase sirtuin-1, OTTHUMP00000198111, OTTHUMP00000198112, RP11-57G10.3, SIRT 1, SIRT-1, regulatory protein SIR2 homolog 1, SIR2-like protein 1, sirtuin type 1, unnamed protein product, yeast silent information regulator 2 (Sir2p) homolog
UniProt ID (Human) Q96EB6
