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Human Semaphorin 6B quantitates human Semaphorin 6B in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Semaphorin 6B.
The SEMA6B gene encodes semaphorin 6B, which belongs to the semaphorin family of proteins known for their roles in guiding axonal development and modulating cellular signaling pathways. Semaphorin 6B primarily functions in the nervous system where it influences axonal guidance, neuronal development, and synapse formation through interactions with neuropilin and plexin receptor complexes. These interactions are crucial during neural development, ensuring proper neuronal wiring and the establishment of functional neural circuits. In addition to its key role in neural connectivity, SEMA6B is increasingly recognized for its involvement in immune responses, where it can modulate the activity and migration of immune cells. In cancer biology, altered expression of SEMA6B has been implicated in tumor progression, affecting tumor cell adhesion and migration, thereby influencing metastasis. Research continues to explore the specific mechanisms of SEMA6B's action and how it can be targeted for therapeutic interventions in neural and cancer-related diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : SEM-SEMA-Y, SEMA-VIB, SEMA6B, SEMAN, SEMAZ, UNQ1907/PRO4353
基因ID : (Human) 10501
基因符号 : SEMA6B
蛋白别名 : sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B, Sema Z, semaphorin VIB, semaphorin Z, Semaphorin-6B, semaphorin-6Ba, Semaphorin-Z
UniProt ID (Human) Q9H3T3