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Invitrogen
Human TDP43 ELISA Kit
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产品规格
检测灵敏度
0.19 ng/mL
测定范围
0.31-20
检测样本类型/体积
{Plasma=100 µL, Serum=100 µL}
手工操作时间
1 hr 20 min
总时间
2 hr 30 min
均相（无需洗涤）
No
批间差异
<10%
批内差异
<10%
检测仪器
Absorbance Microplate Reader
产品规格
96 Tests
产品成分
Pre-coated microwell plate
Standard
Biotinylated Detection Antibody
Streptavidin-HRP
Standard and Sample Diluent
Biotinylated Detection Antibody Diluent
HRP Conjugate Diluent
Wash Buffer Concentrate
Stop Solution
Substrate Solutio
Adhesive Plate Covers
Standard
Biotinylated Detection Antibody
Streptavidin-HRP
Standard and Sample Diluent
Biotinylated Detection Antibody Diluent
HRP Conjugate Diluent
Wash Buffer Concentrate
Stop Solution
Substrate Solutio
Adhesive Plate Covers
运输条件
Wet ice
储存
At 2-8°C for one year. Protect from light. Do not freeze.
蛋白名称
TDP-43
均相（无需洗涤）
Human
检测试剂盒格式
Sandwich ELISA Kit
检测抗体结合物
Biotin
标签或染料
HRP
关于本试剂盒
The Human TDP43 (TAR DNA Binding Protein 43) ELISA quantitates TDP43 in serum, plasma, and other biological fluids.
靶标信息
TDP43 was first identified as a novel cellular protein that binds to HIV-1 virus TAR DNA sequence motifs and acts a transcriptional repressor to the HIV-1 LTR. Later experiments revealed that TDP43 also regulates the splicing of exon 9 of the cystic fibrosis transmembrane conductance regular (CFTR), most likely through the association with the UG repeats at the 3"e; splice site. A hyperphosphorylated, ubiquitinated, and cleaved form of TDP43 known as pathologic TDP43 is the major disease protein in ubiquitin-positive, tau-, and alpha-synuclein-negative frontotemporal dementia (FLTD-U). TDP43 is not related to TRBP1, and RNA binding protein that binds HIV-1 TAR RNA sequences.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
基因别名 : ALS10, TARDBP, TDP-43, TDP43
基因ID : (Human) 23435
基因符号 : TARDBP
蛋白别名 : OTTHUMP00000002171, OTTHUMP00000002173, RP4-635E18.2, TAR DNA-binding protein 43, TAR DNA-binding protein-43, TDP-43
UniProt ID (Human) Q13148
