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Human Thrombospondin-5/COMP quantitates human Thrombospondin-5/COMP in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Thrombospondin-5/COMP.
COMP is a noncollagenous extracellular matrix protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : CTS2, EDM1, EPD1, MED, PSACH, THBS5, TSP-5, TSP5
基因ID : (Human) 1311
基因符号 : COMP
蛋白别名 : cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple), MGC131819, MGC149768, Thrombospondin5, TSP 5, multiple epiphyseal dysplasia, pseudoachondroplasia (epiphyseal dysplasia 1, thrombospondin-5, unnamed protein product
UniProt ID (Human) P49747