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The Human Thrombospondin-5/COMP Rapid ELISA Kit quantitates COMP in serum and plasma
COMP is a noncollagenous extracellular matrix protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : COMP, CTS2, EDM1, EPD1, MED, PSACH, THBS5, TSP-5, TSP5
基因ID : (Human) 1311
基因符号 : COMP
蛋白别名 : Cartilage oligomeric matrix protein, cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple), COMP, MGC131819, MGC149768, Thrombospondin5, TSP 5, multiple epiphyseal dysplasia, pseudoachondroplasia (epiphyseal dysplasia 1, Thrombospondin-5, TSP5, unnamed protein product
UniProt ID (Human) P49747