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Human Troponin C quantitates human Troponin C in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human Troponin C.
Troponin (Tn) is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments, and as a result of calcium-ion uptake by troponin-C, the elements of the muscle thin filament undergo a series of allosteric changes which allow the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : CMD1Z, CMH13, TN-C, TNC, TNNC
基因ID : (Human) 7134
基因符号 : TNNC1
蛋白别名 : cardiac 3, Cardiac troponin I, CMD1FF, CMD2A, CMH7, MGC116817, Troponin I, Troponin I cardiac, TroponinI, RCM1, Tn1, Tni, TNN I3, TNNC 1, TNNI3, cardiac troponin C, slow twitch skeletal/cardiac muscle troponin C, TNNC1, troponin C type 1 (slow), unnamed protein product
UniProt ID (Human) P63316