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Human ULBP-2/ALCAN-alpha/N2DL2 quantitates human ULBP-2/ALCAN-alpha/N2DL2 in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human ULBP-2/ALCAN-alpha/N2DL2.
ULBP2 encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : ALCAN-alpha, N2DL2, NKG2DL2, RAET1H, ULBP2, UNQ463/PRO791
基因ID : (Human) 80328
基因符号 : ULBP2
蛋白别名 : ALCAN-alpha, N2DL-2, NKG2D ligand 2, Retinoic acid early transcript 1H, UL16-binding protein 2
UniProt ID (Human) Q9BZM5