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Human hCG-beta quantitates human hCG-beta in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant human hCG-beta.
hCG beta is the beta chain of hCG (Human chorionic gonadotropin), a 40 kDa glycoprotein hormone produced by trophoblastic cells of the placenta beginning 10 to 12 days after conception. hCG is made up of alpha and beta subunits that are non-covalently associated. The alpha subunit is similar to those found on the pituitary hormones FSH, LH ans TSH. However, the beta subunit is different in FSH, LH and TSH and are involved in conferring biological specificity. Maintenance of the fetus in the first trimester of pregnancy requires the production of hCG, which binds to the corpus luteum of the ovary which is stimulated to produce progesterone which in turn maintains the secretory endometrium. hCG is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha and Beta subunits. The alpha subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). Diseases associated with Hcg dysfunction include gestational trophoblastic tumor and hydatidiform mole, recurrent 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
基因别名 : CG-beta, CGB
基因ID : (Human) 1082
基因符号 : CGB3
蛋白别名 : chorionic gonadotrophin chain beta, chorionic gonadotropin beta 3 subunit, chorionic gonadotropin beta chain, chorionic gonadotropin beta subunit 3, chorionic gonadotropin chain beta, chorionic gonadotropin human, FSH-alpha, human chorionic gonadotropin, LSH-alpha, TSH-alpha, chorionic gonadotropin, beta polypeptide, unnamed protein product
UniProt ID (Human) P0DN86